hrp0084p3-1001 | Gonads | ESPE2015

Anti-Müllerian Hormone is a Useful Marker of Gonadotoxicity in Girls Treated for Cancer: A Prospective Study

Miyoshi Yoko , Yasuda Kie , Miyamura Takako , Miyashita Emiko , Hashii Yoshiko , Ozono Keiichi

Background: Gonadal dysfunction is one of the major endocrinological late effects among cancer survivors. Chemotherapeutic agents and radiation are so gonadotoxic that ovarian reserve diminishes. Measurement of anti-müllerian hormone (AMH) concentration is useful as a marker of ovarian reserve or gonadal deficiency in female childhood cancer survivors (CCSs), particularly among patients without high gonadotropin levels.Objective and hypotheses: The ...